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SAG 21k
CAS No. 946002-48-8
SAG 21k( —— )
Catalog No. M34770 CAS No. 946002-48-8
SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 178 | In Stock |
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| 5MG | 275 | In Stock |
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| 10MG | 411 | In Stock |
|
| 25MG | 678 | In Stock |
|
| 50MG | 908 | In Stock |
|
| 100MG | 1305 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSAG 21k
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NoteResearch use only, not for human use.
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Brief DescriptionSAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.
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DescriptionHh agonist 1 (compound 21k) is a potent Hedgehog (Hh) agonist, with an EC50 0.3 nM. Hh agonist 1 can be used for the research of stroke and other neurological disorders.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetHedgehog (Hh)
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RecptorHedgehog/Smoothened
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Research Area——
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Indication——
Chemical Information
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CAS Number946002-48-8
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Formula Weight556.07
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Molecular FormulaC29H28ClF2N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESClC=1C=2C(SC1C(N(CC3=C(OC)C=CC(=C3)C=4C=CN=CC4)[C@H]5CC[C@H](NC)CC5)=O)=C(F)C=CC2F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brunton SA, et al. Potent agonists of the Hedgehog signaling pathway. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4308-11. ?
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